Although this book is entitled Biomaterials: The Intersection of Biology and Materials Science, we believe that this field has evolved over approximately the past fifty years from the intersection of multiple disparate viewpoints, including materials science, biology, engineering, and clinical, business, and regulatory perspectives. With this history, the multidisciplinary nature of biomaterials is inescapable. As educators in this field, we have taken on the particular challenge of preparing students with a broad range of backgrounds to address the complex issues associated with designing and implementing new biomedical devices. With this in mind, we set out to write a balanced and cohesive textbook that would introduce fundamental concepts of biomaterials to undergraduate engineering majors in their second year of study or later. Given this target audience, the text assumes basic knowledge of chemistry and physics, but does not require in-depth exposure to more complex mathematical concepts such as partial differential equations, or any knowledge of cell biology or biochemistry.