This fifth edition of Simulation with Arena has the same goal as the first four editions: to provide an introduction to simulation using Arena. It is intended to be used as an entry-level simulation text, most likely in a first course on simulation at the undergraduate or beginning graduate level. However. material from the later chapters could be incorporated into a second, graduate-level course. The book can also be used to learn simulation independent of a formal course (more specifically, by Arena users). The objective is to present the concepts and methods of simulation using Arena as a vehicle to help the reader reach the point of being able to carry out effective simulation modeling, analysis, and projects using the Arena simulation system. While we´ll cover most of the capabilities of Arena, the book is not meant to be an exhaustive reference on the software, which is fully documented in its extensive online reference and help system.